Nystatin Topical Powder

Prescription

Brand names: KLAYESTA

Dosage Form

Topical

Route

TOPICAL

Manufacturer

Epic Pharma, LLC

About This Medication

DESCRIPTION Nystatin is a polyene antifungal antibiotic obtained from Streptomyces noursei. The molecular formula for Nystatin is C 47 H 75 NO 17 . The molecular weight of Nystatin is 926.09. Structural formula: KLAYESTA is for dermatologic use. KLAYESTA contains 100,000 USP nystatin units per gram. Inactive ingredients: magnesium stearate and light kaolin. structural-formula.jpg

Active Ingredients

Ingredient	Strength
Nystatin	-

Indications & Usage

INDICATIONS AND USAGE KLAYESTA is indicated in the treatment of cutaneous or mucocutaneous mycotic infections caused by Candida albicans and other susceptible Candida species. KLAYESTA is not indicated for systemic, oral, intravaginal or ophthalmic use.

Dosage & Administration

DOSAGE AND ADMINISTRATION Very moist lesions are best treated with the topical dusting powder. Adults and Pediatric Patients (Neonates and Older) Apply to candidal lesions two or three times daily until healing is complete. For fungal infection of the feet caused by Candida species, the powder should be dusted on the feet, as well as, in all foot wear.

Side Effects Overview

ADVERSE REACTIONS The frequency of adverse events reported in patients using KLAYESTA is less than 0.1%. The more common events that were reported include allergic reactions, burning, itching, rash, eczema, and pain on application. (See PRECAUTIONS, General .)

Contraindications

CONTRAINDICATIONS KLAYESTA is contraindicated in patients with a history of hypersensitivity to any of its components.

Pharmacokinetics

Pharmacokinetics KLAYESTA is not absorbed from intact skin or mucous membrane.

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External Resources

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Source: openfda

Last updated: 2026-03-19

Frequently Asked Questions

INDICATIONS AND USAGE KLAYESTA is indicated in the treatment of cutaneous or mucocutaneous mycotic infections caused by Candida albicans and other susceptible Candida species. KLAYESTA is not indicated for systemic, oral, intravaginal or ophthalmic use.

DOSAGE AND ADMINISTRATION Very moist lesions are best treated with the topical dusting powder. Adults and Pediatric Patients (Neonates and Older) Apply to candidal lesions two or three times daily until healing is complete. For fungal infection of the feet caused by Candida species, the powder should be dusted on the feet, as well as, in all foot wear.

CONTRAINDICATIONS KLAYESTA is contraindicated in patients with a history of hypersensitivity to any of its components.

Nystatin Topical Powder is a prescription medication. You will need a valid prescription from a licensed healthcare provider.

References & Data Sources

• DailyMed — Nystatin Topical Powder drug label (National Library of Medicine)
• openFDA — Nystatin Topical Powder label data (U.S. Food & Drug Administration)
• RxNorm — RXCUI 646456 (NLM Normalized Drug Names)
• NDC Directory — Nystatin Topical Powder (FDA National Drug Code)

Medical Disclaimer

The information on this page is intended for educational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment.

Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or medication.

Data sources: DailyMed (NLM), openFDA, MFDS