Trifluridine
PrescriptionBrand names: Trifluridine
About This Medication
DESCRIPTION: Trifluridine Ophthalmic Solution (also known as trifluorothymidine, F 3 TdR, F 3 T), an antiviral drug for topical treatment of epithelial keratitis caused by herpes simplex virus. The chemical name of trifluridine is α,α,α-trifluorothymidine. Trifluridine has the following structural formula. Trifluridine sterile ophthalmic solution contains 1% trifluridine in an aqueous solution with acetic acid and sodium acetate (buffers), sodium chloride, and thimerosal 0.001% (added as a preservative). The pH range is 5.5 to 6.0 and osmolality is approximately 283 mOsm. chemical
Active Ingredients
| Ingredient | Strength |
|---|---|
| Trifluridine | - |
Indications & Usage
Dosage & Administration
Side Effects Overview
Warnings & Precautions
WARNINGS: The recommended dosage and frequency of administration should not be exceeded (See DOSAGE AND ADMINISTRATION ).
Contraindications
CONTRAINDICATIONS: Trifluridine Ophthalmic Solution is contraindicated for patients who develop hypersensitivity reactions or chemical intolerance to trifluridine.
Frequently Asked Questions
INDICATIONS AND USAGE: Trifluridine Ophthalmic Solution is indicated for the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to herpes simplex virus, types 1 and 2.
DOSAGE AND ADMINISTRATION: Instill one drop of Trifluridine Ophthalmic Solution onto the cornea of the affected eye every 2 hours while awake for a maximum daily dosage of nine drops until the cornea ulcer has completely re-epithelialized. Following re-epithelialization, treatment for an additional 7 days of one drop every 4 hours while awake for a minimum daily dosage of five drops is recommended. If there are no signs of improvement after 7 days of therapy or complete re-epithelialization has not …
WARNINGS: The recommended dosage and frequency of administration should not be exceeded (See DOSAGE AND ADMINISTRATION ).
CONTRAINDICATIONS: Trifluridine Ophthalmic Solution is contraindicated for patients who develop hypersensitivity reactions or chemical intolerance to trifluridine.
Trifluridine is a prescription medication. You will need a valid prescription from a licensed healthcare provider.
Similar Drops Products
Browse all Drops products →References & Data Sources
- • DailyMed — Trifluridine drug label (National Library of Medicine)
- • openFDA — Trifluridine label data (U.S. Food & Drug Administration)
- • RxNorm — RXCUI 313477 (NLM Normalized Drug Names)
- • NDC Directory — Trifluridine (FDA National Drug Code)
Medical Disclaimer
The information on this page is intended for educational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment.
Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or medication.
Data sources: DailyMed (NLM), openFDA, MFDS