💊 Medications 🩺 Pathologies ⚠ Interactions 📚 Guides
All Medications Classes de Médicaments Pathologies Fabricants Effets Indésirables
Guides Glossaire Outils Chronologie Ce jour-là
🇺🇸 English 🇰🇷 한국어 🇯🇵 日本語 🇨🇳 中文简体 🇪🇸 Español 🇧🇷 Português 🇮🇳 हिन्दी 🇸🇦 العربية 🇫🇷 Français 🇷🇺 Русский 🇩🇪 Deutsch 🇹🇷 Türkçe 🇻🇳 Tiếng Việt 🇮🇩 Bahasa Indonesia 🇹🇭 ไทย
Ces informations sont fournies à des fins éducatives uniquement. Consultez toujours un professionnel de santé. En savoir plus

Therapeutic Index

TI

Définition

The ratio between the toxic dose and the therapeutic dose of a drug (TD50/ED50). A narrow therapeutic index means there is a small margin between the dose that produces the desired effect and the dose that causes toxicity, requiring careful dosing and monitoring.

Exemple

Lithium has a narrow therapeutic index (blood levels of 0.6-1.2 mEq/L are therapeutic, while levels above 1.5 mEq/L can be toxic), requiring regular blood monitoring.

Termes Associés

ED50 ED50 LD50 LD50 Therapeutic Drug Monitoring TDM

Mentionné dans les Guides