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Adverse Drug Reaction

ADR

Definição

An unintended and harmful response to a medication at normal therapeutic doses. ADRs range from mild (nausea, headache) to severe (anaphylaxis, organ damage). Type A reactions are dose-dependent and predictable; Type B reactions are idiosyncratic and unpredictable.

Exemplo

Statins can cause myalgia (Type A, dose-dependent muscle pain) and rarely rhabdomyolysis (severe muscle breakdown).

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