Sulconazole Nitrate
Prescriptionชื่อทางการค้า: Exelderm
About This Medication
DESCRIPTION EXELDERM (sulconazole nitrate, USP) CREAM, 1.0% is a broad-spectrum antifungal agent intended for topical application. Sulconazole nitrate, USP, the active ingredient in EXELDERM CREAM, is an imidazole derivative with in vitro antifungal and antiyeast activity. Its chemical name is (±)-1-[2,4-dichloro- β -[( p -chlorobenzyl)-thiol]-phenethyl]imidazole mononitrate and it has the following chemical structure: Sulconazole nitrate, USP is a white to off-white crystalline powder with a molecular weight of 460.77. It is freely soluble in pyridine; slightly soluble in ethanol, acetone, and chloroform; and very slightly soluble in water. It has a melting point of about 130°C. EXELDERM CREAM contains sulconazole nitrate, USP 10 mg/g in an emollient cream base consisting of propylene glycol, stearyl alcohol, isopropyl myristate, cetyl alcohol, polysorbate 60, sorbitan mono-stearate, glyceryl stearate (and) PEG-100 stearate, ascorbyl paImitate, and purified water, with sodium hydroxide and/or nitric acid added to adjust the pH. Chemical Structure
ส่วนประกอบออกฤทธิ์
| ส่วนประกอบ | ความแรง |
|---|---|
| Sulconazole Nitrate | - |
ข้อบ่งใช้และการใช้งาน
ขนาดยาและวิธีการให้ยา
Side Effects Overview
ข้อห้ามใช้
CONTRAINDICATIONS EXELDERM (sulconazole nitrate, USP) CREAM, 1.0% is contraindicated in patients who have a history of hypersensitivity to any of its ingredients.
Frequently Asked Questions
INDICATIONS AND USAGE EXELDERM (sulconazole nitrate, USP) CREAM, 1.0% is an antifungal agent indicated for the treatment of tinea pedis (athlete's foot), tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagro-phytes, Epidermophyton floccosum, and Microsporum canis,* and for the treatment of tinea versicolor. *Efficacy for this organism in the organ system was studied in fewer than ten infections.
DOSAGE AND ADMINISTRATION A small amount of cream should be gently massaged into the affected and surrounding skin areas once or twice daily, except in tinea pedis, where administration should be twice daily. Early relief of symptoms is experienced by the majority of patients and clinical improvement may be seen fairly soon after treatment is begun; however, tinea corporis/cruris and tinea versicolor should be treated for 3 weeks and tinea pedis for 4 weeks to reduce the possibility of recurrence. …
CONTRAINDICATIONS EXELDERM (sulconazole nitrate, USP) CREAM, 1.0% is contraindicated in patients who have a history of hypersensitivity to any of its ingredients.
Sulconazole Nitrate is a prescription medication. You will need a valid prescription from a licensed healthcare provider.
Similar Topical Products
Browse all Topical products →References & Data Sources
- • DailyMed — Sulconazole Nitrate drug label (National Library of Medicine)
- • openFDA — Sulconazole Nitrate label data (U.S. Food & Drug Administration)
- • RxNorm — RXCUI 106366 (NLM Normalized Drug Names)
- • NDC Directory — Sulconazole Nitrate (FDA National Drug Code)
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แหล่งข้อมูล: DailyMed (NLM), openFDA, MFDS