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Bacitracin Zinc And Polymyxin B Sulfates

Prescription

Tên thương mại: polycin

Dạng bào chế
Drops
Đường dùng
OPHTHALMIC
Nhà sản xuất
NuCare Pharmaceuticals,Inc.

About This Medication

DESCRIPTION: Bacitracin Zinc and Polymyxin B Sulfate Ophthalmic Ointment USP, is a sterile antimicrobial ointment for ophthalmic use. Each gram contains: bacitracin zinc equivalent to 500 bacitracin units, polymyxin B sulfate equivalent to 10,000 polymyxin B units, mineral oil, and white petrolatum. Bacitracin zinc is the zinc salt of bacitracin, a mixture of related cyclic polypeptides (mainly bacitracin A) produced by the growth of an organism of the licheniformis group of Bacillus subtilis var Tracy. It has a potency of not less than 40 bacitracin units per mg. The structural formula for bacitracin A is: Polymyxin B sulfate is the sulfate salt of polymyxin B 1 and B 2 which are produced by the growth of Bacillus polymyxa (Prazmowski) Migula (Fam. Bacillaceae ). It has a potency of not less than 6,000 polymyxin B units per mg, calculated on an anhydrous basis. The structural formulae are: Structural Formula Image 1 Structural Formula Image 2

Hoạt chất

Thành phần Hàm lượng
Bacitracin Zinc -
Polymyxin B Sulfate -

Chỉ định & Cách dùng

INDICATIONS AND USAGE: Polycin® Ophthalmic Ointment is indicated for the topical treatment of superficial infections of the external eye and its adnexa caused by susceptible bacteria. Such infections encompass conjunctivitis, keratitis and keratoconjunctivitis, blepharitis and blepharoconjunctivitis.

Liều dùng & Cách dùng

DOSAGE AND ADMINISTRATION: May be applied every 3 or 4 hours for 7 to 10 days, depending on the severity of the infection.

Side Effects Overview

ADVERSE REACTIONS: Adverse reactions have occurred with the anti-infective components Bacitracin Zinc and Polymyxin B Sulfate Ophthalmic Ointment. The exact incidence is not known. Reactions occurring most often are allergic sensitization reactions including itching, swelling, and conjunctival erythema (see WARNINGS ). More serious hypersensitivity reactions, including anaphylaxis, have been reported rarely. Local irritation on instillation has also been reported. To report SUSPECTED ADVERSE REACTIONS, contact Perrigo at 1-866-634-9120 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Cảnh báo & Thận trọng

Chống chỉ định

Frequently Asked Questions

INDICATIONS AND USAGE: Polycin® Ophthalmic Ointment is indicated for the topical treatment of superficial infections of the external eye and its adnexa caused by susceptible bacteria. Such infections encompass conjunctivitis, keratitis and keratoconjunctivitis, blepharitis and blepharoconjunctivitis.

DOSAGE AND ADMINISTRATION: May be applied every 3 or 4 hours for 7 to 10 days, depending on the severity of the infection.

WARNINGS: NOT FOR INJECTION INTO THE EYE. Bacitracin Zinc and Polymyxin B Sulfate Ophthalmic Ointment should never be directly introduced into the anterior chamber of the eye. Ophthalmic ointments may retard corneal wound healing. Topical antibiotics may cause cutaneous sensitization. A precise incidence of hypersensitivity reactions (primarily skin rash) due to topical antibiotics is not known. The manifestations of sensitization to topical antibiotics are usually itching, reddening, and edema of the conjunctiva and eyelid. A sensitization reaction may manifest simply, …

CONTRAINDICATIONS: Polycin® Ophthalmic Ointment is contraindicated in individuals who have shown hypersensitivity to any of its components.

Bacitracin Zinc And Polymyxin B Sulfates is a prescription medication. You will need a valid prescription from a licensed healthcare provider.

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References & Data Sources

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Nguồn dữ liệu: DailyMed (NLM), openFDA, MFDS

Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.