Erythromycin Topical Solution 2%
PrescriptionTên thương mại: erythromycin topical solution 2%
About This Medication
DESCRIPTION Erythromycin topical solution, USP 2% contains erythromycin, USP for topical dermatologic use. Erythromycin is a macrolide antibiotic produced from a strain of Saccaropolyspora erythraea (formerly Streptomyces erythreus ). It is a base and readily forms salts with acids. Chemically, erythromycin is: (3 R *,4 S *,5 S *,6 R *,7 R *,9 R *,11 R *,12 R *,13 S *,14 R *)-4-[(2,6-Dideoxy-3- C -methyl-3- 0 -methyl-α-L- ribo -hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy -3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-ß-D- xylo -hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione. It has the following structural formula: Molecular Formula: C 37 H 67 NO 13 Molecular Weight: 733.94 Erythromycin, USP is a white or slightly yellow, crystalline powder that is soluble in water, alcohol, chloroform and in ether. Each mL of erythromycin topical solution, USP 2% contains 20 mg of erythromycin base in a vehicle consisting of alcohol (66%), citric acid, and propylene glycol. formula
Hoạt chất
| Thành phần | Hàm lượng |
|---|---|
| Erythromycin | - |
Chỉ định & Cách dùng
Liều dùng & Cách dùng
Side Effects Overview
Cảnh báo & Thận trọng
WARNINGS Pseudomembranous colitis has been reported with nearly all antibacterial agents, including erythromycin, and may range in severity from mild to life-threatening. Therefore, it is important to consider this diagnosis in patients who present with diarrhea subsequent to the administration of antibacterial agents. Treatment with antibacterial agents alters the normal flora of the colon and may permit overgrowth of clostridia. Studies indicate that a toxin produced by Clostridium difficile is one primary cause of “antibiotic-associated colitis”. After the diagnosis of pseudomembranous colitis has been established, therapeutic measures should be initiated. Mild cases of pseudomembranous colitis usually respond to drug discontinuation alone. In moderate to severe cases, consideration should be given to management with fluids and electrolytes, protein supplementation and treatment with an antibacterial drug clinically effective against C. difficile colitis.
Chống chỉ định
CONTRAINDICATIONS Erythromycin topical solution, 2% is contraindicated in those individuals who have shown hypersensitivity to any of its components.
Frequently Asked Questions
INDICATIONS AND USAGE Erythromycin topical solution, 2% is indicated for the topical treatment of acne vulgaris.
DOSAGE AND ADMINISTRATION Erythromycin topical solution, 2% should be applied over the affected areas twice a day (morning and evening) after the skin is thoroughly washed with warm water and soap and patted dry. Acne lesions on the face, neck, shoulders, chest, and back may be treated in this manner. This medication should be applied with applicator top. If fingertips are used, wash hands after application. Drying and peeling may be controlled by reducing the frequency of applications.
WARNINGS Pseudomembranous colitis has been reported with nearly all antibacterial agents, including erythromycin, and may range in severity from mild to life-threatening. Therefore, it is important to consider this diagnosis in patients who present with diarrhea subsequent to the administration of antibacterial agents. Treatment with antibacterial agents alters the normal flora of the colon and may permit overgrowth of clostridia. Studies indicate that a toxin produced by Clostridium difficile is one primary cause of “antibiotic-associated colitis”. After the diagnosis of …
CONTRAINDICATIONS Erythromycin topical solution, 2% is contraindicated in those individuals who have shown hypersensitivity to any of its components.
Erythromycin Topical Solution 2% is a prescription medication. You will need a valid prescription from a licensed healthcare provider.
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Browse all Topical products →References & Data Sources
- • DailyMed — Erythromycin Topical Solution 2% drug label (National Library of Medicine)
- • openFDA — Erythromycin Topical Solution 2% label data (U.S. Food & Drug Administration)
- • RxNorm — RXCUI 318202 (NLM Normalized Drug Names)
- • NDC Directory — Erythromycin Topical Solution 2% (FDA National Drug Code)
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Nguồn dữ liệu: DailyMed (NLM), openFDA, MFDS