Therapeutic Drug Monitoring
TDMDefinición
The measurement of drug concentrations in blood at specific times to optimize individual dosing. TDM is essential for drugs with narrow therapeutic indices, significant pharmacokinetic variability, or serious toxicity. Common drugs requiring TDM include lithium, vancomycin, aminoglycosides, and immunosuppressants.
Ejemplo
Vancomycin trough levels are measured before the next dose to ensure they remain within the therapeutic range (15-20 mcg/mL for serious infections).
Términos Relacionados
Mencionado en Guías
-
Managing Multiple Medications SafelyA comprehensive guide to safely managing polypharmacy — keeping an accurate medication list, working with pharmacists, understanding medication reconciliation, and …
-
Drug-Induced Kidney DamageThe kidneys are the primary route of elimination for many drugs, making them vulnerable to drug-induced injury. This guide covers …
-
How Immunosuppressants WorkImmunosuppressants are used in organ transplantation and autoimmune diseases to prevent the immune system from attacking the body or a …
-
Therapeutic Drug Monitoring (TDM)For some medications, measuring drug levels in blood is the most reliable way to confirm the dose is right. Learn …
-
Complete Guide to Thyroid MedicationsAn informative guide to medications for hypothyroidism and hyperthyroidism — covering levothyroxine, antithyroid drugs, and the importance of therapeutic monitoring …
-
Medications and Kidney DiseaseHow chronic kidney disease affects drug clearance, which drugs accumulate to dangerous levels in kidney disease, and how renal dosing …
-
Pharmacogenomics: Your Genes and Your DrugsYour DNA affects how your body processes medications. Pharmacogenomics explains why the same drug can work differently from one person …