Extended Release

ER/XR

Définition

A drug formulation designed to release the active ingredient gradually over an extended period, allowing less frequent dosing. Extended-release tablets should not be crushed or chewed, as this destroys the controlled-release mechanism and can cause dangerous dose dumping.

Exemple

Metoprolol ER is taken once daily, while immediate-release metoprolol requires dosing 2-3 times per day.

Termes Associés

Steady State Css Peak Plasma Concentration Cmax Immediate Release IR

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