Enzyme Induction
Definição
The process by which a drug increases the production of metabolizing enzymes (particularly CYP450), leading to faster breakdown of itself or other drugs. This can reduce the effectiveness of co-administered medications. Induction typically takes days to weeks to develop fully.
Exemplo
Rifampin is a potent CYP3A4 inducer that can reduce the effectiveness of oral contraceptives, potentially leading to unintended pregnancy.
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