Synergism

คำจำกัดความ

An interaction where the combined effect of two drugs is greater than the sum of their individual effects. Synergism can be therapeutically beneficial (combining antibiotics) or dangerous (combining sedatives with alcohol).

ตัวอย่าง

Trimethoprim-sulfamethoxazole (Bactrim) is a synergistic antibiotic combination — each drug inhibits a different step in bacterial folic acid synthesis, making the combination far more effective than either drug alone.

คำที่เกี่ยวข้อง

Dose-Response Curve Antagonism (Drug Interaction) Polypharmacy

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