Taper
Định nghĩa
The gradual reduction of a drug dose over time to prevent withdrawal symptoms or rebound effects. Abrupt discontinuation of certain drugs (corticosteroids, benzodiazepines, antidepressants, opioids) can cause serious or dangerous withdrawal syndromes.
Ví dụ
After long-term prednisone use, the dose is tapered gradually (e.g., reducing by 5 mg per week) to allow the adrenal glands to resume natural cortisol production.